Summary
| Production Name | CDKN2A/p16INK4a Rabbit Monoclonal Antibody |
| Description | Recombinant rabbit monoclonal antibody |
| Host | Rabbit |
| Application | WB,ICC/IF |
| Reactivity | Human,Mouse |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Purification | Affinity Purification |
Immunogen
| Gene Name | CDKN2A |
| Alternative Names | CDKN2A; CDKN2; MTS1; Cyclin-dependent kinase inhibitor 2A; isoforms 1/2/3; Cyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4A |
| Gene ID | 1029 |
| SwissProt ID | P42771 |
Application
| Dilution Ratio | WB 1:500-1:1000,ICC/IF 1:50-1:200 |
| Molecular Weight | Calculated MW: 17 kDa; Observed MW: 17 kDa |
Background
p16-INK4A a cell-cycle regulatory protein that Interacts with CDK4 and CDK6, inhibiting their ability to interact with cyclins D. Inhibits the phosphorylation of the retinoblastoma protein by CDK4 or CDK6. Four alternatively spliced isoforms have been reported.
Research Area
Cell Biology