Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody($99/20μL)
Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody($99/20μL)
Size:20μL Price:$99
Size:50μL Price:$150
Size:100μL Price:$280
Size:200μL Price:$520
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:CHEK2
SKU: APRab03382
Detail

Summary

Production Name

Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody

Description

Rabbit polyclonal Antibody

Host

Rabbit

Application

WB,IHC,ICC/IF

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purification

 

Immunogen

Gene Name

CHEK2

Alternative Names

CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2

Gene ID

11200

SwissProt ID

O96017

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200

Molecular Weight

Calculated MW: 61 kDa; Observed MW: 61 kDa

 

Background

These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.

 

Research Area

Epigenetics and Nuclear Signaling

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