Product List

TNF alpha (9D9) Mouse Monoclonal Antibody

Size:50μL Price:$150
Size:100μL Price:$280
Size:200μL Price:$520
Application:WB,IHC
Reactivity:Human,Rat,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:TNF

SKU: AMM00896

Detail

Summary

Production Name	TNF alpha (9D9) Mouse Monoclonal Antibody
Description	Mouse monoclonal Antibody
Host	Mouse
Application	WB,IHC
Reactivity	Human,Rat,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purification

Immunogen

Gene Name	TNF
Alternative Names	TNF; TNFA; TNFSF2; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a
Gene ID	7124
SwissProt ID	P01375

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight	Calculated MW: 26 kDa; Observed MW: 17,25 kDa

Background

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Research Area

Immunology