Summary
| Production Name | Ku80 (8H1) Mouse Monoclonal Antibody |
| Description | Mouse monoclonal Antibody |
| Host | Mouse |
| Application | WB,ICC/IF,IP,ChIP |
| Reactivity | Human,Monkey |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | XRCC5 |
| Alternative Names | XRCC5; G22P2; X-ray repair cross-complementing protein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair pr |
| Gene ID | 7520 |
| SwissProt ID | P13010 |
Application
| Dilution Ratio | WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50,ChIP 1:20 |
| Molecular Weight | Calculated MW: 83 kDa; Observed MW: 86 kDa |
Background
Ku80 the 80-kilodalton subunit of the Ku complex, also known as ATP-dependant DNA helicase II. A single stranded DNA-dependent ATP-dependent helicase. It functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events.
Research Area
Epigenetics and Nuclear Signaling