Summary
| Production Name | RPA70 (8C3) Mouse Monoclonal Antibody |
| Description | Mouse monoclonal Antibody |
| Host | Mouse |
| Application | WB,ICC/IF,IP |
| Reactivity | Human,Monkey,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | RPA1 |
| Alternative Names | RPA1; HSSB; MST075; REPA1; RF-A; RP-A; RPA70 |
| Gene ID | 6117 |
| SwissProt ID | P27694 |
Application
| Dilution Ratio | WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50 |
| Molecular Weight | Calculated MW: 68 kDa; Observed MW: 68 kDa |
Background
Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.
Research Area
Epigenetics and Nuclear Signaling