Product List

CDK5 (2E8) Mouse Monoclonal Antibody

Size:50μL Price:$168
Size:100μL Price:$300
Size:200μL Price:$520
Application:WB,ICC/IF
Reactivity:Human,Mouse,Rat,Monkey
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:CDK5

SKU: AMM03453

Detail

Summary

Production Name	CDK5 (2E8) Mouse Monoclonal Antibody
Description	Mouse monoclonal Antibody
Host	Mouse
Application	WB,ICC/IF
Reactivity	Human,Mouse,Rat,Monkey

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purification

Immunogen

Gene Name	CDK5
Alternative Names	Cdk 5; Cdk5; CDK5_HUMAN; Cell division protein kinase 5; Crk6; Cyclin dependent kinase 5; Cyclin-dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; Serine threonine protein kinase PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit.
Gene ID	1020
SwissProt ID	Q00535

Application

Dilution Ratio	WB 1:500-1:1000,ICC/IF 1:50-1:200
Molecular Weight	Calculated MW: 33 kDa; Observed MW: 36 kDa

Background

Activated by cyclins but by p35 (CDK5R1) and p39. An important regulator of neuronal positioning during brain development. May also play a role in synaptogenesis and neurotransmission. Substrates include TAU, MAP2, NF-H and -M, Nudel, PDE6, beta-catenin, amphyphysin, dynamin I, synapsin 1, Munc-18, and NMDA receptor 2A. Plays a role in myogenesis, haematopoietic cell differentiation, spermatogenesis, insulin secretion, and lens differentiation.

Research Area

Cell Biology