Product List

Phospho-Bad (S112) (4M2) Rabbit Monoclonal Antibody

Size:50μL Price:$128
Size:100μL Price:$230
Size:200μL Price:$380
Application:WB,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:BAD

SKU: AMRe05858

Detail

Summary

Production Name	Phospho-Bad (S112) (4M2) Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IP
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Phosphorylated
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification	Affinity purification

Immunogen

Gene Name	BAD
Alternative Names	BAD; BBC2; BBC6; BCL2L8;
Gene ID	572
SwissProt ID	Q92934

Application

Dilution Ratio	WB 1:1000-1:5000,IP 1:20-1:50
Molecular Weight	18kDa

Background

Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Research Area

Cell Biology