TriMethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody

TriMethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody

Size1:50μl Price1:$188
Size2:100μl Price2:$338
Size3:500μl Price3:$1200 SKU: AMRe02834 Category: Methyl Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

TriMethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF

Reactivity

Human,Rat

 

Performance

Conjugation

Unconjugated

Modification

Methylated

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

H3C1

Alternative Names

H3K27me3; H3 histone; HIST1H3A; Histone cluster 1; H3a

Gene ID

8350

SwissProt ID

P68431

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Molecular Weight

Calculated MW: 15 kDa; Observed MW: 15 kDa

 

Background

H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

 

Research Area

Epigenetics and Nuclear Signaling

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