EGFR Rabbit Monoclonal Antibody
EGFR Rabbit Monoclonal Antibody
EGFR Rabbit Monoclonal Antibody
Size:50μL Price:158 $99
Size:100μL Price:288 $180
Application:WB,IHC,IP
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:EGFR
SKU: AMRe04076
Detail

Summary

Production Name

EGFR Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,IP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

EGFR

Alternative Names

EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

Gene ID

1956

SwissProt ID

P00533

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50

Molecular Weight

Calculated MW: 134 kDa; Observed MW: 175 kDa

 

Background

EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

 

Research Area

Signal Transduction

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