Summary
| Production Name | IDH1 (2P17) Rabbit Monoclonal Antibody |
| Description | Recombinant rabbit monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC,FC,IP,IF-P |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Purification | Affinity purification |
Immunogen
| Gene Name | IDH1 |
| Alternative Names | HEL-216; HEL-S-26; ICDH; IDCD; IDH; IDH1; IDP; IDPC; PICD; |
| Gene ID | 3417 |
| SwissProt ID | O75874 |
Application
| Dilution Ratio | WB 1:500-1:2000,IHC 1:500-1:1000,FC 1:50-1:100,IP 1:20-1:50,IF-P 1:500-1:1000 |
| Molecular Weight | 47kDa |
Background
Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
Research Area
Signal Transduction