Product List

TIMELESS Rabbit Monoclonal antibody

Size:50μL Price:168 $99
Size:100μL Price:300 $180
Application:WB,IHC,ICC/IF
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:TIMELESS

SKU: AMRe02691

Detail

Summary

Production Name	TIMELESS Rabbit Monoclonal antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,ICC/IF
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purified

Immunogen

Gene Name	TIMELESS
Alternative Names	hTIM; TIM; TIM1; Timeless; timeless circadian clock 1; TIMELESS1
Gene ID	8914
SwissProt ID	Q9UNS1

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200
Molecular Weight	Calculated MW: 139 kDa; Observed MW: 150 kDa

Background

Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus.

Research Area

Epigenetics and Nuclear Signaling