Summary
| Production Name | TGF beta 1 (8F6) Mouse Monoclonal Antibody |
| Description | Mouse monoclonal Antibody |
| Host | Mouse |
| Application | WB,IHC |
| Reactivity | Human,Rat,Mouse |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | TGFB1 |
| Alternative Names | TGF beta 1; TGFB; CED; LAP |
| Gene ID | 7040 |
| SwissProt ID | P01137 |
Application
| Dilution Ratio | WB 1:500-1:1000,IHC 1:50-1:100 |
| Molecular Weight | Calculated MW: 44 kDa; Observed MW: 12,25,45-65 kDa |
Background
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Research Area
Cardiovascular