| Name | Recombinant Human IL-21 |
| Purity | Greater than 95% as determined by reducing SDS-PAGE |
| Endotoxin level | <0.01 EU/µg as determined by LAL test. |
| Construction | Recombinant Human Interleukin-21 is produced by our E.coli expression system and the target gene encoding Gln30-Ser162 is expressed. |
| Accession # | Q9HBE4 |
| Host | E.coli |
| Species | Human |
| Predicted Molecular Mass | 15.6 KDa |
| Buffer | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Form | Lyophilized |
| Shipping | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| Stability&Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Alternative Names
Interleukin-21; IL-21; Za11; IL21
Background
IL-21 induces the production of IgG1 and IgG3 in B-cells. IL-21 may promote the transition between innate and adaptive immunity. IL-21 may have a role in proliferation and maturation of natural killer cells in synergy with IL15. IL-21 stimulates interferon gamma production in T-cells and natural killer cells by synergy with IL15 and IL18. Dysregulation of IL-21 has a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases.
Note
For Research Use Only , Not for Diagnostic Use.