| Name | Recombinant Human IL-1b |
| Purity | Greater than 95% as determined by reducing SDS-PAGE |
| Endotoxin level | <0.01 EU/µg as determined by LAL test. |
| Construction | Recombinant Human Interleukin-1 Beta is produced by our E.coli expression system and the target gene encoding Ala117-Ser269 is expressed. |
| Accession # | P01584 |
| Host | E.coli |
| Species | Human |
| Predicted Molecular Mass | 17.5 KDa |
| Buffer | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150 mM NaCl,3% Trehalose,0.02% Tween 80,4% Mannitol,pH 7.4. |
| Form | Lyophilized |
| Shipping | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| Stability&Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Alternative Names
Interleukin-1 beta; Catabolin; IL1F2; IL1B
Background
IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Note
For Research Use Only , Not for Diagnostic Use.