Recombinant Mouse IL-15RA (C-Fc)

Recombinant Mouse IL-15RA (C-Fc)

Size1:10μg price1:$58
Size2:50μg price2:$108
Size3:500μg price3:$690
SKU: PHM0873 Category: Cytokines Tags: ,

Datasheet

Name

Recombinant Mouse IL-15RA (C-Fc)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Mouse Interleukin-15 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Gly33-Lys205 is expressed with a human IgG1 Fc tag at the C-terminus.

Accession #

Q60819

Host

Human Cells

Species

Mouse

Predicted Molecular Mass

45.5 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Interleukin-15 receptor subunit alpha; Il15ra; sIL-15 receptor subunit alpha

 

Background

Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.

 

Note

For Research Use Only , Not for Diagnostic Use.