Name: MLKL Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe04148
Price: 158 USD
Availability: InStock
Rating: 5 (1 reviews)

MLKL Rabbit Monoclonal Antibody

Cat: AMRe04148

Size:50μL Price:$158
Size:100μL Price:$288
Size:200μL Price:$520
Application:WB,IHC
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MLKL Category: Recombinant Monoclonal Antibody Tags: Unconjugated, Signal Transduction, Rabbit, WB, IHC, Human, Mouse

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Summary

Production Name	MLKL Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC
Reactivity	Human,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	Affinity Chromatography

Immunogen

Gene Name	MLKL
Alternative Names	MLKL
Gene ID	197259
SwissProt ID	Q8NB16

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight	Calculated MW: 54 kDa; Observed MW: 54 kDa

Background

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Research Area

Signal Transduction