CCD80_RAT Q6QD51
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UniProt:Q6QD51
Recommended name:Coiled-coil domain-containing protein 80
EC number:
Alternative names:
Cleaved into:
GeneID:64387
Gene names (primary ):Ccdc80
Gene names (synonym ):Dro1, Ssg1
Gene names (ORF ):
Length:949
Mass:107,691
Sequence:MTWKMGPHFTMLLAMWLVCGSASQSSALDSDGRPGRKVPLASPISSRSARYLRHTGRSGGVEKSTQEEPNPQSFQRRKSVPVLRLAHPTVRPPPSGINGAPVRPELKPIARGSASEMVRDEGSSARTRMLRFPSGSSSPNILASFAGKNRVWVISAPHASEGYYRLMMSLLKDDVYCELAERHIQQIVLFHQAGEEGGKVRRITSEGQILEQPLDPNLIPKLMSFLKLEKGKFSMVLLKKTLQVEERYPYPVRLEAMYEVIDQGPIRRIEKIRQKGFVQKCKASGIEGHVVQEGNNGGGGGGSTGLGSDKRKEDPRRTQIHPTREPPRKQTTTKAATPQPPPTPRATTLPPAPVTTATRATSRVVTVAARPTTTTAYPATQRPWTSRLHPFSVSHRPPATAEMTTVRGPSVSEQLYPLPRKEQQREKPQATRRPNKATNYGSFTATPPTTLWEGSTRAVGTSRFRDNRTDKREHGHQDPNVVPGPHKPIKGKLPKKKEKILSNEYEAKYDLSRPTTSQGEEELQVDNIPSQNAKESKKHEKPEKPEKEKKKKGKSAKPDKLLRSEKQMKKAEKKSKQEKEKTKKKKAGKTEQDDYQKPTAKHLAPSPRKSVADLLGSFEGKRRLLLITTPKAENNMYVQQRDEYLESFCKMATRRISVVTIFGPVNNSSMKIDHFQLDNEKPMRVVDDEDLVDQHLISELRKEYGMTYNDFFMVLTDVDLRVKQYYEVPIAMKSVFDLIDTFQSRIKDMEKQKKEGITCKEDKRQSLENFLSRFRWRRRLLVISAPNDEDWAYSQQLSALNGQACNFGLRHITILKLLGVGEEVGGILELFPINGSSTVEREDVPAHLVKDIRNYFQVSPEYFSMLLVGKDGNVKSWYPSPMWSMVIVYDLIDSMQLRRQEMAIQQSLGMRCPEDEYAGYGYHSYHQGYQDGYQDDYRHHESYHHGYPY
Tissue specificity:Isoform 2 is expressed in uterus, liver, lung, spleen, kidney, heart, bladder, skeletal muscle and brain (at protein level). Isoform 2 is expressed very low in mammary gland and intestine (at protein level). Isoform 2 is expressed in lactating mammary glands and mammary tumors (at protein level). Ubiquitous (isoform 1). Isoform 2 is expressed in ovary, uterus, mammary glands, liver, lung, spleen, kidney, heart, bladder, intestine, skeletal muscle and brain. 2 s
Induction:
Developmental stage:Down-regulated by oncogenes (isoform 1). Isoform 2 is down-regulated by beta estradiol in mammary gland (at mRNA level). Isoform 2 is up-regulated by beta estradiol in mammary glands (at protein level). Up-regulated in lactating mammary glands and mammary tumors (at protein level). 2 s
Protein families: