FMR1_RAT Q80WE1
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UniProt:Q80WE1
Recommended name:Fragile X messenger ribonucleoprotein 1 Curated
EC number:
Alternative names:
Cleaved into:
GeneID:
Gene names (primary ):Fmr1
Gene names (synonym ):
Gene names (ORF ):
Length:593
Mass:66,780
Sequence:MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPERQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLEVPEDLRQMCAKESAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLILRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKSVPQEEENLPPSSLPSNNSRVGSNSSEEKKHLDTKENTHFSQPNSTKVQRGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKGYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPRETKGRTTDGSLQSTSSEGSRLRTGKDRNQKKEKPDSVDGLQPLVNGVP
Tissue specificity:Expressed in brain (PubMed:9030614). Expressed in neurons (PubMed:9030614). Expressed in mature oligodendrocytes (OLGs) (PubMed:23891804). Expressed in oligodendroglia progenitor cells (OPCs) and immature oligodendrocytes (OLGs) in the neonatal brain (at protein level) (PubMed:14613971). 3 s
Induction:
Developmental stage:Up-regulated in response to the activation of group I metabotropic glutamate receptors at synapses (PubMed:9144248). Rapidly and transiently up-regulated in response to light exposure in the cell bodies and dendrites of visual cortical neurons (at protein level) (PubMed:15564573). 2 s
Protein families: