MK15_HUMAN Q8TD08
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UniProt:Q8TD08
Recommended name:Mitogen-activated protein kinase 15
EC number:EC:2.7.11.24
Alternative names:(MAP kinase 15) (MAPK 15) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)
Cleaved into:
GeneID:225689
Gene names (primary ):MAPK15
Gene names (synonym ):ERK7 ERK8
Gene names (ORF ):
Length:544
Mass:59832
Sequence:MCTVVDPRIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDHPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSDEWAREADVRPRAHEGVQLSVPEYRSRVYQMILECGGSSGTSREKGPEGVSPSQAHLHKPRADPQLPSRTPVQGPRPRPQSSPGHDPAEHESPRAAKNVPRQNSAPLLQTALLGNGERPPGAKEAPPLTLSLVKPSGRGAAPSLTSQAAAQVANQALIRGDWNRGGGVRVASVQQVPPRLPPEARPGRRMFSTSALQGAQGGARALLGGYSQAYGTVCHSALGHLPLLEGHHV
Tissue specificity:Widely expressed with a maximal expression in lung and kidney. {ECO:0000269|PubMed:11875070, ECO:0000269|PubMed:16484222}.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily