STYK1_HUMAN Q6J9G0
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UniProt:Q6J9G0
Recommended name:Tyrosine-protein kinase STYK1
EC number:EC:2.7.10.2
Alternative names:(Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)
Cleaved into:
GeneID:55359
Gene names (primary ):STYK1
Gene names (synonym ):NOK
Gene names (ORF ):
Length:422
Mass:47577
Sequence:MGMTRMLLECSLSDKLCVIQEKQYEVIIVPTLLVTIFLILLGVILWLFIREQRTQQQRSGPQGIAPVPPPRDLSWEAGHGGNVALPLKETSVENFLGATTPALAKLQVPREQLSEVLEQICSGSCGPIFRANMNTGDPSKPKSVILKALKEPAGLHEVQDFLGRIQFHQYLGKHKNLVQLEGCCTEKLPLYMVLEDVAQGDLLSFLWTCRRDVMTMDGLLYDLTEKQVYHIGKQVLLALEFLQEKHLFHGDVAARNILMQSDLTAKLCGLGLAYEVYTRGAISSTQTIPLKWLAPERLLLRPASIRADVWSFGILLYEMVTLGAPPYPEVPPTSILEHLQRRKIMKRPSSCTHTMYSIMKSCWRWREADRPSPRELRLRLEAAIKTADDEAVLQVPELVVPELYAAVAGIRVESLFYNYSML
Tissue specificity:Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers. {ECO:0000269|PubMed:12841579, ECO:0000269|PubMed:15150103, ECO:0000269|PubMed:17298854}.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, Tyr protein kinase family