STYK1_HUMAN   Q6J9G0


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UniProt:Q6J9G0

Recommended name:Tyrosine-protein kinase STYK1

EC number:EC:2.7.10.2

Alternative names:(Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)

Cleaved into:

GeneID:55359

Gene names  (primary ):STYK1

Gene names  (synonym ):NOK

Gene names  (ORF ):

Length:422

Mass:47577

Sequence:MGMTRMLLECSLSDKLCVIQEKQYEVIIVPTLLVTIFLILLGVILWLFIREQRTQQQRSGPQGIAPVPPPRDLSWEAGHGGNVALPLKETSVENFLGATTPALAKLQVPREQLSEVLEQICSGSCGPIFRANMNTGDPSKPKSVILKALKEPAGLHEVQDFLGRIQFHQYLGKHKNLVQLEGCCTEKLPLYMVLEDVAQGDLLSFLWTCRRDVMTMDGLLYDLTEKQVYHIGKQVLLALEFLQEKHLFHGDVAARNILMQSDLTAKLCGLGLAYEVYTRGAISSTQTIPLKWLAPERLLLRPASIRADVWSFGILLYEMVTLGAPPYPEVPPTSILEHLQRRKIMKRPSSCTHTMYSIMKSCWRWREADRPSPRELRLRLEAAIKTADDEAVLQVPELVVPELYAAVAGIRVESLFYNYSML

Tissue specificity:Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers. {ECO:0000269|PubMed:12841579, ECO:0000269|PubMed:15150103, ECO:0000269|PubMed:17298854}.

Induction:

Developmental stage:

Protein families:Protein kinase superfamily, Tyr protein kinase family


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