ABC3B_HUMAN Q9UH17
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UniProt:Q9UH17
Recommended name：DNA dC->dU-editing enzyme APOBEC-3B
EC number：EC:3.5.4.38
Alternative names：(A3B) (Phorbolin-1-related protein) (Phorbolin-2/3)
Cleaved into：
GeneID：9582
Gene names (primary )：APOBEC3B
Gene names (synonym )：
Gene names (ORF )：
Length：382
Mass：45924
Sequence：MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVYFKPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVTIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCNEAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
Tissue specificity：Expressed at high and moderate levels in peripheral blood leukocytes, spleen, testes, heart, thymus, prostate and ovary. Also expressed at low levels in several other tissues. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:20308164}.
Induction：Phorbol 12-myristate 13-acetate (PMA) induces overexpression in keratinocytes. Up-regulated by IFN-alpha. {ECO:0000269|PubMed:10469298}.
Developmental stage：
Protein families：Cytidine and deoxycytidylate deaminase family