CR3L2_HUMAN Q70SY1
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UniProt:Q70SY1
Recommended name：Cyclic AMP-responsive element-binding protein 3-like protein 2
EC number：
Alternative names：(cAMP-responsive element-binding protein 3-like protein 2) (BBF2 human homolog on chromosome 7)
Cleaved into：Processed cyclic AMP-responsive element-binding protein 3-like protein 2
GeneID：64764
Gene names (primary )：CREB3L2
Gene names (synonym )：BBF2H7
Gene names (ORF )：
Length：520
Mass：57415
Sequence：MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEKSVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQSPFTHITTSDSFNDDEVESEKWYLSTDFPSTSIKTEPVTDEPPPGLVPSVTLTITAISTPLEKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSDSEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRTLIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGWDRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELDRRVNTTF
Tissue specificity：Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels in heart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected in brain and heart. {ECO:0000269|PubMed:12915480}.
Induction：Up-regulated by ER stress at the transcript and protein levels, the increase at the protein level is much higher than at the transcript level. This induction is accompanied by increased proteolytic cleavage that releases the N-terminal transcription factor domain. {ECO:0000269|PubMed:17178827}.
Developmental stage：
Protein families：BZIP family, ATF subfamily