TGFI1_HUMAN O43294
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UniProt:O43294
Recommended name:Transforming growth factor beta-1-induced transcript 1 protein
EC number:
Alternative names:(Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5)
Cleaved into:
GeneID:7041
Gene names (primary ):TGFB1I1
Gene names (synonym ):ARA55
Gene names (ORF ):
Length:461
Mass:49814
Sequence:MEDLDALLSDLETTTSHMPRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG
Tissue specificity:Expressed in platelets, smooth muscle and prostate stromal cells (at protein level). {ECO:0000269|PubMed:10075738, ECO:0000269|PubMed:10708479, ECO:0000269|PubMed:11311131, ECO:0000269|PubMed:12642630, ECO:0000269|PubMed:12772188, ECO:0000269|PubMed:16849583, ECO:0000269|PubMed:17166536, ECO:0000269|PubMed:17233630, ECO:0000269|PubMed:9664039}.
Induction:Up-regulated by TNF and hydrogen peroxide. {ECO:0000269|PubMed:11489729, ECO:0000269|PubMed:11532379}.
Developmental stage:
Protein families:Paxillin family