FFAR4_HUMAN Q5NUL3
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UniProt:Q5NUL3
Recommended name:Free fatty acid receptor 4
EC number:
Alternative names:(G-protein coupled receptor 120) (G-protein coupled receptor 129) (G-protein coupled receptor GT01) (G-protein coupled receptor PGR4) (Omega-3 fatty acid receptor 1)
Cleaved into:
GeneID:338557
Gene names (primary ):FFAR4
Gene names (synonym ):GPR120 GPR129 O3FAR1 PGR4
Gene names (ORF ):
Length:361
Mass:40494
Sequence:MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
Tissue specificity:[Isoform 2]: The predominant isoform in human tissues. Expressed in adipose tissue, pancreatic islets, lung and brain. Expressed in alpha cells of pancreatic islets (PubMed:24742677). Expressed in primary cilia of perivascular preadipocytes of white adipose tissue (at protein level) (PubMed:31761534). {ECO:0000269|PubMed:24742677, ECO:0000269|PubMed:31761534}.; Abundant expression in the intestinal tract. Expressed in colonic intraepithelial neuroendocrine cells. {ECO:0000269|PubMed:15619630}.
Induction:
Developmental stage:[Isoform 2]: Low expression is detected in preadipocytes, mainly localized in primary cilium. {ECO:0000305|PubMed:31761534}.
Protein families:G-protein coupled receptor 1 family