GNT2A_HUMAN Q8N0V5
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UniProt:Q8N0V5
Recommended name:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase
EC number:EC:2.4.1.150
Alternative names:(N-acetylglucosaminyltransferase) (I-branching enzyme) (IGNT)
Cleaved into:
GeneID:2651
Gene names (primary ):GCNT2
Gene names (synonym ):GCNT5 II NACGT1
Gene names (ORF ):
Length:402
Mass:45873
Sequence:MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYPTENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMPQNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVASEVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHKNSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHFWVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNSPSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF
Tissue specificity:Isoform B is expressed in lens epithelium cells. Isoform C is expressed in reticulocytes. {ECO:0000269|PubMed:12424189, ECO:0000269|PubMed:12468428}.
Induction:
Developmental stage:Expression of isoform B increases dramatically during development and oncogenesis. {ECO:0000269|PubMed:7579796}.
Protein families:Glycosyltransferase 14 family