GPER1_MOUSE Q8BMP4
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UniProt:Q8BMP4
Recommended name:G-protein coupled estrogen receptor 1
EC number:
Alternative names:(Chemoattractant receptor-like 2) (G protein-coupled estrogen receptor 1) (G-protein coupled receptor 30) (Membrane estrogen receptor) (mER)
Cleaved into:
GeneID:76854
Gene names (primary ):Gper1
Gene names (synonym ):Cmkrl2 Gper Gpr30
Gene names (ORF ):
Length:375
Mass:42479
Sequence:MDATTPAQTVGVEIYLGPVWPAPSNSTPLALNLSLALREDAPGNLTGDLSEHQQYVIALFLSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAAADLILVADSLIEVFNLDEQYYDIAVLCTFMSLFLQINMYSSVFFLTWMSFDRYLALAKAMRCGLFRTKHHARLSCGLIWMASVSATLVPFTAVHLRHTEEACFCFADVREVQWLEVTLGFIMPFAIIGLCYSLIVRALIRAHRHRGLRPRRQKALRMIFAVVLVFFICWLPENVFISVHLLQWTQPGDTPCKQSFRHAYPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYVEQKTSLPALNRFCHATLKAVIPDSTEQSEVRFSSAV
Tissue specificity:Expressed in brain, heart, spleen, preadipocytes, mature adipocytes and primary hippocampal neurons. Expressed in neurons of the hippocampus, hypothalamic paraventricular nucleus (PVH), supraoptic nucleus (SON) and the median eminence. Expressed in the nucleus ambiguous (at protein level). Expressed in brain, pituitary gland, adrenal medulla, renal pelvis, ovary, endothelial cells, visceral fat tissues and islets of Langerhans. {ECO:0000269|PubMed:19420011, ECO:0000269|PubMed:21273787, ECO:0000269|PubMed:22306576, ECO:0000269|PubMed:23545157, ECO:0000269|PubMed:23674134, ECO:0000269|PubMed:23871778}.
Induction:Up-regulated during adipogenesis. {ECO:0000269|PubMed:23871778}.
Developmental stage:
Protein families:G-protein coupled receptor 1 family