HYPDH_MOUSE Q8VCZ9
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UniProt:Q8VCZ9
Recommended name:Hydroxyproline dehydrogenase
EC number:EC 1.5.5.3
Alternative names:(HYPDH) (Kidney and liver proline oxidase 1) (MmPOX1) (Probable proline dehydrogenase 2) (Probable proline oxidase 2) (Proline oxidase-like protein) (PO) (Proline oxidase)
Cleaved into:
GeneID:56189
Gene names (primary ):Prodh2
Gene names (synonym ):Hypdh
Gene names (ORF ):
Length:456
Mass:50723
Sequence:MIWTRLPLYGPSKPSTGGWQPLRFDGGAFHVKGTAELARALLVLRLCAWPPLVTHGLAFQAWSQRLLGSRLSGALLRASIYGQFVAGETAEEVRNCVGQLQALGLQPLLAVPTEEEPDSTAKTSEVWYEENLSAMLRCVDLSRALVDAHGPARNSLMQLKVTALASTRLCKELSAWIQRPRGSSELSPERLAEAMDSGRNLQLSCLSTEQNQHLQASLSRLHRVAQHARAKCVRLLVDAEYTFINPALSLLVAALAVRWNSPEEGGPWVWNTYQAYLKDTHQRLEQDAEAAHKAGLAFGVKLVRGAYLDKERSMTQLQGKEDCTQPDYEATSRSYSRCLELMLRCVSNHGPPCHLMVASHNEESVRQATKRMWELGIPLDGPVCFGQLLGMCDHVSLALGQAGYMVYKSIPYGCLEEVIPYLIRRAQENRSVLQGARREQALLSQELWRRLLGRTA
Tissue specificity:
Induction:In liver, by TCF1 and HNF4A. {ECO:0000269|PubMed:15581617}.
Developmental stage:Expressed in liver at 14 dpc. Expression level increases at P5 and decreases after P21. {ECO:0000269|PubMed:15581617}.
Protein families:Proline oxidase family