ZIC2_MOUSE Q62520
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UniProt:Q62520
Recommended name:Zinc finger protein ZIC 2
EC number:
Alternative names:(Zinc finger protein of the cerebellum 2)
Cleaved into:
GeneID:
Gene names (primary ):Zic2
Gene names (synonym ):
Gene names (ORF ):
Length:530
Mass:54954
Sequence:MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAFKLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPPEQHGPHASQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGAGSGSSGSGGGSAAGSGGGGGGAGGGGGGSSGGGSGTTGGHSGLSSNFNEWYV
Tissue specificity:CNS. A high level expression is seen in the cerebellum.
Induction:
Developmental stage:Expressed in the ipsilateral retinal ganglion cells (iRGCs) of the peripheral ventrotemporal (VT) neural retina, during the outgrowth of the uncrossed retinal projection between 16.5 and 18.5 dpc (at protein level). Expression is down-regulated as RGCs extend toward chiasmatic midline at the optic chiasm. {ECO:0000269|PubMed:13678579, ECO:0000269|PubMed:20676059}.
Protein families:GLI C2H2-type zinc-finger protein family