CLOCK_RAT Q9WVS9
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UniProt:Q9WVS9
Recommended name:Circadian locomoter output cycles protein kaput
EC number:EC:2.3.1.48
Alternative names:rCLOCK
Cleaved into:
GeneID:
Gene names (primary ):Clock
Gene names (synonym ):
Gene names (ORF ):
Length:862
Mass:97,004
Sequence:MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSETVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGVEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQSINSQSVGSSLTQPAMSQAANLPIPQGMSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNLGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQQTLQSTSTQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQQPQSQQSSQDQPHPSVQQPAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLTDPSKVQPQ
Tissue specificity:Expressed in the suprachiasmatic nucleus (SCN), and in the piriform cortex (PC). 1
Induction:
Developmental stage:Without light exposure, high levels at ZT6 and low levels at ZT18 and ZT22. Light exposure increases levels in the SCN in phase dependent manner. Levels increased significantly during the subjective night (ZT10-20). In the piriform cortex, levels increased by light at ZT14. 1
Protein families: