FADS1_RAT Q920R3
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UniProt:Q920R3
Recommended name:Acyl-CoA (8-3)-desaturase Curated
EC number:EC:1.14.19.44
Alternative names:Delta(5) fatty acid desaturase (D5D By Similarity; Delta(5) desaturase By Similarity; Delta-5 desaturase 1 Publication) Fatty acid desaturase 1 By Similarity
Cleaved into:
GeneID:84575
Gene names (primary ):Fads1 1 Publication
Gene names (synonym ):
Gene names (ORF ):
Length:447
Mass:52,482
Sequence:MAPDPVQTPDPASAQLRQMRYFTWEEVAQRSGREKERWLVIDRKVYNISDFSRRHPGGSRVISHYAGQDATDPFVAFHINKGLVRKYMNSLLIGELAPEQPSFEPTKNKALTDEFRELRATVERMGLMKANHLFFLFYLLHILLLDVAAWLTLWIFGTSLVPFTLCAVLLSTVQAQAGWLQHDFGHLSVFSTSTWNHLVHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPLFFALGKVLSVELGKEKKKHMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVVQRKKWVDLAWMLSFYVRVFFTYMPLLGLKGLLCLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNVDWVSTQLQATCNVHQSAFNNWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKYGIKYESKPLLTAFADIVYSLKESGQLWLDAYLHQ
Tissue specificity:Highly abundant in adrenal gland and mammary tissue and moderately in liver, kidney, lung, spleen, thymus, brain, and eye. 1
Induction:
Developmental stage:Regulated by dietary vitamin A and exogenous retinoic acid in liver. 1
Protein families:fatty acid desaturase type 1 family