S27A2_HUMAN O14975
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UniProt:O14975
Recommended name:Very long-chain acyl-CoA synthetase
EC number:EC:6.2.1.-
Alternative names:(VLACS) (VLCS) (Arachidonate--CoA ligase) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (Phytanate--CoA ligase) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)
Cleaved into:
GeneID:11001
Gene names (primary ):SLC27A2
Gene names (synonym ):ACSVL1 FACVL1 FATP2 VLACS
Gene names (ORF ):
Length:620
Mass:70312
Sequence:MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL
Tissue specificity:Expressed in liver, kidney, placenta and pancreas. {ECO:0000269|PubMed:10198260, ECO:0000269|PubMed:21768100, ECO:0000269|PubMed:24269233}.
Induction:
Developmental stage:
Protein families:ATP-dependent AMP-binding enzyme family