NKX31_HUMAN   Q99801


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UniProt:Q99801

Recommended name:Homeobox protein Nkx-3.1

EC number:

Alternative names:(Homeobox protein NK-3 homolog A)

Cleaved into:

GeneID:4824

Gene names  (primary ):NKX3-1

Gene names  (synonym ):NKX3.1 NKX3A

Gene names  (ORF ):

Length:234

Mass:26350

Sequence:MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW

Tissue specificity:Highly expressed in the prostate and, at a lower level, in the testis. {ECO:0000269|PubMed:9226374, ECO:0000269|PubMed:9537602}.

Induction:By androgens and, in the LNCaP cell line, by estrogens. Androgenic control may be lost in prostate cancer cells during tumor progression from an androgen-dependent to an androgen-independent phase. {ECO:0000269|PubMed:11137288, ECO:0000269|PubMed:9226374, ECO:0000269|PubMed:9537602}.

Developmental stage:

Protein families:NK-3 homeobox family


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