NKX31_HUMAN Q99801
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UniProt:Q99801
Recommended name:Homeobox protein Nkx-3.1
EC number:
Alternative names:(Homeobox protein NK-3 homolog A)
Cleaved into:
GeneID:4824
Gene names (primary ):NKX3-1
Gene names (synonym ):NKX3.1 NKX3A
Gene names (ORF ):
Length:234
Mass:26350
Sequence:MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW
Tissue specificity:Highly expressed in the prostate and, at a lower level, in the testis. {ECO:0000269|PubMed:9226374, ECO:0000269|PubMed:9537602}.
Induction:By androgens and, in the LNCaP cell line, by estrogens. Androgenic control may be lost in prostate cancer cells during tumor progression from an androgen-dependent to an androgen-independent phase. {ECO:0000269|PubMed:11137288, ECO:0000269|PubMed:9226374, ECO:0000269|PubMed:9537602}.
Developmental stage:
Protein families:NK-3 homeobox family