B2LA1_HUMAN Q16548
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UniProt:Q16548
Recommended name:Bcl-2-related protein A1
EC number:
Alternative names:(Bcl-2-like protein 5) (Bcl2-L-5) (Hemopoietic-specific early response protein) (Protein BFL-1) (Protein GRS)
Cleaved into:
GeneID:597
Gene names (primary ):BCL2A1
Gene names (synonym ):BCL2L5 BFL1 GRS HBPA1
Gene names (ORF ):
Length:175
Mass:20132
Sequence:MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
Tissue specificity:Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
Induction:By phorbol ester and inflammatory cytokines, such as TNF or IL1B/interleukin-1 beta, but not by growth factors.
Developmental stage:
Protein families:Bcl-2 family