SMYD1_HUMAN Q8NB12
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UniProt:Q8NB12
Recommended name：Histone-lysine N-methyltransferase SMYD1
EC number：EC:2.1.1.354
Alternative names：(SET and MYND domain-containing protein 1)
Cleaved into：
GeneID：150572
Gene names (primary )：SMYD1
Gene names (synonym )：
Gene names (ORF )：
Length：490
Mass：56617
Sequence：MTIGRMENVEVFTAEGKGRGLKATKEFWAADIIFAERAYSAVVFDSLVNFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGKVPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHFGEEEQKDLRVDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLNVSEERKRQLKKQYYFDCTCEHCQKKLKDDLFLGVKDNPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNIYMLRMLSIVSEVLSYLQAFEEASFYARRMVDGYMKLYHPNNAQLGMAVMRAGLTNWHAGNIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRVQTEMELRMFRQNEFMYYKMREAALNNQPMQVMAEPSNEPSPALFHKKQ
Tissue specificity：Expression seems mostly restricted to heart and skeletal muscle. {ECO:0000269|PubMed:19783823}.
Induction：By serum response factor SRF and myogenin. SRF binds to the CArG site and MYOG binds to the E-box element on SMYD1 promoter. {ECO:0000269|PubMed:19783823}.
Developmental stage：
Protein families：Class V-like SAM-binding methyltransferase superfamily