SMYD2_HUMAN Q9NRG4
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UniProt:Q9NRG4
Recommended name:N-lysine methyltransferase SMYD2
EC number:EC:2.1.1.-
Alternative names:(HSKM-B) (Histone methyltransferase SMYD2) (Lysine N-methyltransferase 3C) (SET and MYND domain-containing protein 2)
Cleaved into:
GeneID:56950
Gene names (primary ):SMYD2
Gene names (synonym ):KMT3C
Gene names (ORF ):
Length:433
Mass:49688
Sequence:MRAEGLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH
Tissue specificity:
Induction:Expression is repressed by CEBPA. {ECO:0000269|PubMed:17242690}.
Developmental stage:
Protein families:Class V-like SAM-binding methyltransferase superfamily