CASP5_HUMAN P51878
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UniProt:P51878
Recommended name：Caspase-5
EC number：EC:3.4.22.58
Alternative names：(CASP-5) (ICE(rel)-III) (Protease ICH-3) (Protease TY)
Cleaved into：Caspase-5 subunit p20; Caspase-5 subunit p10
GeneID：838
Gene names (primary )：CASP5
Gene names (synonym )：ICH3
Gene names (ORF )：
Length：434
Mass：49736
Sequence：MAEDSGKKKRRKNFEAMFKGILQSGLDNFVINHMLKNNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDTKIEDKALILVDSLRKNRVAHQMFTQTLLNMDQKITSVKPLLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Tissue specificity：Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle. {ECO:0000269|PubMed:7797592}.
Induction：Up-regulated by bacterial lipopolysaccharides (LPS). {ECO:0000269|PubMed:16893518}.
Developmental stage：
Protein families：Peptidase C14A family