PRS33_HUMAN   Q8NF86


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UniProt:Q8NF86

Recommended name:Serine protease 33

EC number:EC:3.4.21.-

Alternative names:(Serine protease EOS)

Cleaved into:

GeneID:260429

Gene names  (primary ):PRSS33

Gene names  (synonym ):

Gene names  (ORF ):

Length:280

Mass:29787

Sequence:MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF

Tissue specificity:Predominantly expressed in macrophages. Present in the spleen, small and large intestine, lung and brain (at protein level). Highly expressed in peripheral leukocytes, ovary, retina, spleen and stomach. Moderately expressed in thymus, uterus and platelets, as well as some brain tissues, such as thalamus and fetal brain. {ECO:0000269|PubMed:12795636}.

Induction:Up-regulated by phorbol myristate acetate (PMA). {ECO:0000269|PubMed:12795636}.

Developmental stage:

Protein families:Peptidase S1 family


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