PRS33_HUMAN Q8NF86
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UniProt:Q8NF86
Recommended name:Serine protease 33
EC number:EC:3.4.21.-
Alternative names:(Serine protease EOS)
Cleaved into:
GeneID:260429
Gene names (primary ):PRSS33
Gene names (synonym ):
Gene names (ORF ):
Length:280
Mass:29787
Sequence:MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
Tissue specificity:Predominantly expressed in macrophages. Present in the spleen, small and large intestine, lung and brain (at protein level). Highly expressed in peripheral leukocytes, ovary, retina, spleen and stomach. Moderately expressed in thymus, uterus and platelets, as well as some brain tissues, such as thalamus and fetal brain. {ECO:0000269|PubMed:12795636}.
Induction:Up-regulated by phorbol myristate acetate (PMA). {ECO:0000269|PubMed:12795636}.
Developmental stage:
Protein families:Peptidase S1 family