EDF1_HUMAN O60869
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UniProt:O60869
Recommended name:Endothelial differentiation-related factor 1
EC number:
Alternative names:(EDF-1) (Multiprotein-bridging factor 1) (MBF1)
Cleaved into:
GeneID:8721
Gene names (primary ):EDF1
Gene names (synonym ):
Gene names (ORF ):
Length:148
Mass:16369
Sequence:MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPRAK
Tissue specificity:Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues. {ECO:0000269|PubMed:10567391, ECO:0000269|PubMed:12040021, ECO:0000269|PubMed:9813014}.
Induction:Down-regulated by HIV-1 Tat or phorbol ester (TPA) treatment in endothelial cells (at mRNA and protein levels). {ECO:0000269|PubMed:9813014}.
Developmental stage:Expressed in fetal tissues. More abundant in kidney. {ECO:0000269|PubMed:9813014}.
Protein families: