ARHG4_MOUSE   Q7TNR9


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UniProt:Q7TNR9

Recommended name:Rho guanine nucleotide exchange factor 4

EC number:

Alternative names:(APC-stimulated guanine nucleotide exchange factor) (Asef)

Cleaved into:

GeneID:226970

Gene names  (primary ):Arhgef4

Gene names  (synonym ):Kiaa1112

Gene names  (ORF ):

Length:484

Mass:56679

Sequence:MDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDYEAPRAGAREADDSGPEAQSCKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKREDMFSEEQLRTIFGNIEDIYRCQKAFVKALEQKFNTERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQRMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKNVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQPQARSQQRMFFLFDRQLIYCKKDLLRRDVLYYKGRLDMDDLEVVDVEDGKDRDLHVSVKNAFRLYCGTTGDSHLLCARKPEQKQRWLKAFAREREQVRLDQETGFSITELQRKQAMLNASKQQATGKPKAVGRPGYLTRHKHPSLPASRPQQQVLVLAEPRRKPSNFWHSISRLAPFRK

Tissue specificity:Expressed in colon epithelial cells. Highly expressed in CNS, including hippocampus, olfactory bulb and cerebellum. Expression is aberrantly enhanced in most colorectal tumors. {ECO:0000269|PubMed:10947987, ECO:0000269|PubMed:19893577}.

Induction:

Developmental stage:

Protein families:


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