ARHG4_MOUSE Q7TNR9
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UniProt:Q7TNR9
Recommended name:Rho guanine nucleotide exchange factor 4
EC number:
Alternative names:(APC-stimulated guanine nucleotide exchange factor) (Asef)
Cleaved into:
GeneID:226970
Gene names (primary ):Arhgef4
Gene names (synonym ):Kiaa1112
Gene names (ORF ):
Length:484
Mass:56679
Sequence:MDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDYEAPRAGAREADDSGPEAQSCKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKREDMFSEEQLRTIFGNIEDIYRCQKAFVKALEQKFNTERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQRMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKNVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQPQARSQQRMFFLFDRQLIYCKKDLLRRDVLYYKGRLDMDDLEVVDVEDGKDRDLHVSVKNAFRLYCGTTGDSHLLCARKPEQKQRWLKAFAREREQVRLDQETGFSITELQRKQAMLNASKQQATGKPKAVGRPGYLTRHKHPSLPASRPQQQVLVLAEPRRKPSNFWHSISRLAPFRK
Tissue specificity:Expressed in colon epithelial cells. Highly expressed in CNS, including hippocampus, olfactory bulb and cerebellum. Expression is aberrantly enhanced in most colorectal tumors. {ECO:0000269|PubMed:10947987, ECO:0000269|PubMed:19893577}.
Induction:
Developmental stage:
Protein families: