SKAP2_MOUSE Q3UND0
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UniProt:Q3UND0
Recommended name:Src kinase-associated phosphoprotein 2
EC number:
Alternative names:(Pyk2/RAFTK-associated protein) (SKAP55 homolog) (SKAP-HOM) (Src family-associated phosphoprotein 2) (Src kinase-associated phosphoprotein 55-related protein) (Src-associated adapter protein with PH and SH3 domains)
Cleaved into:
GeneID:54353
Gene names (primary ):Skap2
Gene names (synonym ):Prap Ra70 Saps Scap2 Skap55r
Gene names (ORF ):
Length:358
Mass:40712
Sequence:MPNPSCTSSPGPLPEEIRNLLADVETFVADTLKGENLSKKAKEKRESLIKKIKDVKSVYLQEFQDKGDAEDGDEYDDPFAGPADTISLASERYDKDDDGPSDGNQFPPIAAQDLPFVIKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYDVRMNNTLRKDGKKDCCFEICAPDKRIYQFTAASPKDAEEWVQQLKFILQDLGSDVIPEDDEERGELYDDVDHPAAVSSPQRSQPIDDEIYEELPEEEEDTASVKMDEQGKGSRDSVHHTSGDKSTDYANFYQGLWDCTGALSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYLMEMYDI
Tissue specificity:Expressed in kidney, lung, liver, spleen, bone marrow and testis. Present in T-cells, B-cells, and all cells of the myelomonocytic lineage. Present in all brain regions, with highest levels in neurons from the Purkinje cell layer, hippocampal gyrus, cortex and substantia nigra (at protein level). {ECO:0000269|PubMed:11063873, ECO:0000269|PubMed:12893833, ECO:0000269|PubMed:15894167, ECO:0000269|PubMed:16135797}.
Induction:By IL-6 in myeloid cells. {ECO:0000269|PubMed:11063873}.
Developmental stage:
Protein families:SKAP family