TRML4_MOUSE Q3LRV9
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UniProt:Q3LRV9
Recommended name：Trem-like transcript 4 protein
EC number：
Alternative names：(TLT-4) (Triggering receptor expressed on myeloid cells-like protein 3) (Triggering receptor expressed on myeloid cells-like protein 4)
Cleaved into：
GeneID：224840
Gene names (primary )：Treml4
Gene names (synonym )：TLT4 Treml3
Gene names (ORF )：
Length：263
Mass：29355
Sequence：MAWRYSQLLLVPVQLVFLASVCCPGVWGSTVSEELHRMVGQSLSVQCQYKPKEESYVLKTWCRQTAPSKCTRVVTTSEPRKAARELQHTIWDDPEAGFFNITMTQLTEDDSAFYWCGPYYPSLREVTVLRNISLVVSPAPSTLPSQTIAPLPESTATIFMPFPVLTTSPEETTDSSINGTGHRNQSSSSPGWTSPGLLVSVQYGLLLLKALMLSVFCVLLCWRSGQGREYMAETMELSKLPHISKSLDTVSHISGYEKKANWY
Tissue specificity：Predominantly expressed in spleen, with highest levels on selected populations of macrophages, including red pulp macrophages, and on subsets of dendritic cells (DC), mostly on CD8alpha(+) DC (at protein level) (PubMed:19155473, PubMed:22210914, PubMed:25848864). Also expressed on blood and spleen Ly6C(low) monocytes (at protein level) (PubMed:22210914). Not expressed on lymphocytes or granulocytes (at protein level) (PubMed:19155473, PubMed:22210914). {ECO:0000269|PubMed:19155473, ECO:0000269|PubMed:22210914, ECO:0000269|PubMed:25848864}.
Induction：Induced by synthetic TLR7 ligand gardiquimod (GRD) in cultured splenic macrophages. {ECO:0000269|PubMed:25848864}.
Developmental stage：
Protein families：