CP1B1_MOUSE Q64429
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UniProt:Q64429
Recommended name：Cytochrome P450 1B1
EC number：EC 1.14.14.1
Alternative names：(CYPIB1) (Cytochrome P450CMEF) (Cytochrome P450EF) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
Cleaved into：
GeneID：13078
Gene names (primary )：Cyp1b1
Gene names (synonym )：Cyp1-b1
Gene names (ORF )：
Length：543
Mass：60537
Sequence：MATSLSADSPQQLSSLSTQQTTLLLLFSVLAAVHLGQWLLRQWQRKPWSSPPGPFPWPLIGNAAAVGQASHLYFARLARRYGDVFQIRLGSCPVVVLNGESAIHQALVQQGSIFADRPPFASFRVVSGGRSLAFGHYSEHWKTQRRSAYSTMRAFSTRHPRSRGLLEGHALAEARELVAVLVRRCAGGAFLDPTQPVIVAVANVMSAVCFGCRYNHDDAEFLELLSHNEEFGRTVGAGSLVDVLPWLQLFPNPVRTTFRKFEQLNRNFSNFVLDKFLRHRESLVPGAAPRDMTDAFILSAEKKASGAPGDDSSGLDLEDVPATITDIFGASQDTLSTALLWLLILFTRYPDVQARVQAELDQVVGRDRLPCMSDQPNLPYVMAFLYESMRFSSFLPVTIPHATTANTFVLGYYIPKNTVVFVNQWSVNHDPAKWPNPEDFDPARFLDKDGFINKALASSVMIFSVGKRRCIGEELSKMLLFLFISILAHQCNFKANQNESSNMSFSYGLTIKPKSFRIHVSLRESMELLDNAVKKLQTEEGCK
Tissue specificity：Constitutively expressed in retinal and kidney pericytes cells (PubMed:23568032). Expressed in retinal endothelial cells (at protein level). Expressed in cardiac, pulmonary and aortic endothelial cells (PubMed:19005183). Constitutively expressed in trabecular meshwork of the eye (at protein level) (PubMed:23979599). {ECO:0000269|PubMed:19005183, ECO:0000269|PubMed:23568032, ECO:0000269|PubMed:23979599}.
Induction：Up-regulated by polycyclic aromatic hydrocarbons (PAH) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). {ECO:0000269|PubMed:23568032, ECO:0000269|PubMed:23692925}.
Developmental stage：
Protein families：Cytochrome P450 family