CRLF2_MOUSE   Q8CII9


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UniProt:Q8CII9

Recommended name:Cytokine receptor-like factor 2

EC number:

Alternative names:(Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLP receptor) (Type I cytokine receptor delta 1)

Cleaved into:

GeneID:57914

Gene names  (primary ):Crlf2

Gene names  (synonym ):Crlm2 Tpte2 Tslpr

Gene names  (ORF ):

Length:359

Mass:37762

Sequence:MAWALAVILLPRLLAAAAAAAAVTSRGDVTVVCHDLETVEVTWGSGPDHHGANLSLEFRYGTGALQPCPRYFLSGAGVTSGCILPAARAGLLELALRDGGGAMVFKARQRASAWLKPRPPWNVTLLWTPDGDVTVSWPAHSYLGLDYEVQHRESNDDEDAWQTTSGPCCDLTVGGLDPARCYDFRVRASPRAAHYGLEAQPSEWTAVTRLSGAASAASCTASPAPSPALAPPLLPLGCGLAALLTLSLLLAALRLRRVKDALLPCVPDPSGSFPGLFEKHHGNFQAWIADAQATAPPARTEEEDDLIHPKAKRVEPEDGTSLCTVPRPPSFEPRGPGGGAMVSVGGATFMVGDSGYMTL

Tissue specificity:High level of expression in liver, lung and testis. Also expressed in heart, brain, spleen, thymus and bone marrow. Highly expressed in progenitors and myeloid cells. Isoform 2 is expressed in primary hemotopoietic cells.

Induction:Up-regulated in the myeloid 32D cell line by granulocyte colony-stimulating factor (G-CSF).

Developmental stage:

Protein families:Type I cytokine receptor family, Type 5 subfamily


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