CRLF2_MOUSE Q8CII9
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UniProt:Q8CII9
Recommended name:Cytokine receptor-like factor 2
EC number:
Alternative names:(Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLP receptor) (Type I cytokine receptor delta 1)
Cleaved into:
GeneID:57914
Gene names (primary ):Crlf2
Gene names (synonym ):Crlm2 Tpte2 Tslpr
Gene names (ORF ):
Length:359
Mass:37762
Sequence:MAWALAVILLPRLLAAAAAAAAVTSRGDVTVVCHDLETVEVTWGSGPDHHGANLSLEFRYGTGALQPCPRYFLSGAGVTSGCILPAARAGLLELALRDGGGAMVFKARQRASAWLKPRPPWNVTLLWTPDGDVTVSWPAHSYLGLDYEVQHRESNDDEDAWQTTSGPCCDLTVGGLDPARCYDFRVRASPRAAHYGLEAQPSEWTAVTRLSGAASAASCTASPAPSPALAPPLLPLGCGLAALLTLSLLLAALRLRRVKDALLPCVPDPSGSFPGLFEKHHGNFQAWIADAQATAPPARTEEEDDLIHPKAKRVEPEDGTSLCTVPRPPSFEPRGPGGGAMVSVGGATFMVGDSGYMTL
Tissue specificity:High level of expression in liver, lung and testis. Also expressed in heart, brain, spleen, thymus and bone marrow. Highly expressed in progenitors and myeloid cells. Isoform 2 is expressed in primary hemotopoietic cells.
Induction:Up-regulated in the myeloid 32D cell line by granulocyte colony-stimulating factor (G-CSF).
Developmental stage:
Protein families:Type I cytokine receptor family, Type 5 subfamily