OTOP1_MOUSE Q80VM9
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UniProt:Q80VM9
Recommended name：Proton channel OTOP1
EC number：
Alternative names：(Otopetrin-1)
Cleaved into：
GeneID：21906
Gene names (primary )：Otop1
Gene names (synonym )：
Gene names (ORF )：
Length：600
Mass：65755
Sequence：MPGGPGAPSSPAASSGSSRAAPSGIAACPLSPPPLARGSPQASGPRRGASVPQKLAETLSSQYGLNVFVAGLLFLLAWAVHATGVGKSDLLCVLTALMLLQLLWMLWYVGRSYMQRRLIRPKDTHAGARWLRGSITLFAFITVVLGCLKVAYFIGFSECLSATEGVFPVTHAVHTLLQVYFLWGHAKDIIMSFKTLERFGVIHSVFTNLLLWANSVLNESKHQLNEHKERLITLGFGNITIVLDDHTPQCNCTPPALCSALSHGIYYLYPFNIEYQILASTMLYVLWKNIGRRVDSSQHQKMQCRFDGVLVGSVLGLTVLAATIAVVVVYMIHIGRSKSKSESALIMFYLYAITVLLLMGAAGLVGSWIYRVDEKSLDESKNPARKLDVDLLVATGSGSWLLSWGSILAIACAETRPPYTWYNLPYSVLVIVEKYVQNIFIIESVHLEPEGVPEDVRTLRVVTVCSSEAAALAASTLGSQGMAQDGSPAVNGNLCLQQRCGKEDQESGWEGATGTTRCLDFLQGGMKRRLLRNITAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAAALFEVYCKI
Tissue specificity：Detected in embryonic inner ear macular epithelia (PubMed:12651873). Expressed in thymus, heart, kidney, skin, vestibular system of the inner ear, sour taste cells, brown adipose tissue, heart, uterus, dorsal root ganglion, adrenal gland, lactating mammary gland and stimulated mast cells (PubMed:12651873, PubMed:29371428). Specifically expressed in sour taste cells and not other types of taste cells (PubMed:29371428). {ECO:0000269|PubMed:12651873, ECO:0000269|PubMed:29371428}.
Induction：Up-regulated in white adipose tissue in response to proinflammatory signaling. {ECO:0000269|PubMed:24379350}.
Developmental stage：
Protein families：Otopetrin family