GRHL1_MOUSE Q921D9
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UniProt:Q921D9
Recommended name:Grainyhead-like protein 1 homolog
EC number:
Alternative names:(Transcription factor CP2-like 2) (Transcription factor LBP-32)
Cleaved into:
GeneID:195733
Gene names (primary ):Grhl1
Gene names (synonym ):Mgr Tcfcp2l2
Gene names (ORF ):
Length:618
Mass:70176
Sequence:MTQEYDNKRPVLVLQNEALYPQRRSYTSEDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRERRSSAVKPEGEHPEPEHSKRNSIPNVTEQPLISAGENRVQVLKNVPFNIVLPHSNQLGIDKRGHLTAPDTTVTVSIATMPTHSIKTEIQPHGFAVGIPPAVYHSEPTERVVVFDRSLSTDQFSSGTQPPNAQRRTPDSTFSETFKEGVQEVFFPSELSLRMPGMNSEDYVFDNVSGNNFEYTLEASKSLRQKQGDSTMTYLNKGQFYPVTLKEGSSNEGIHHPISKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHTAKQRCIDIADYKESFNTISNIEEIAYNAISFTWDINDEAKVFISVNCLSTDFSSQKGVKGLPLNIQIDTYSYNNRSNKPVHRAYCQIKVFCDKGAERKIRDEERKQSKRKVSDVKVQLLPSHKRTDITVFKPFLDLDTQPVLFIPDVHFTNLQRGSHVLSLPSEELEGEGSVLKRGPFGTEDDFGVPPPAKLTRTEEPKRVLLYVRKESEEVFDALMLKTPSLKGLMEAISDKYDVPHDKIGKIFKKCKKGILVNMDDNIVKHYSNEDTFQLQIEEAGGSYKLTLTEI
Tissue specificity:Isoform 1 is highly expressed in brain, pancreas, tonsil, placenta and kidney. Isoform 2 is highly expressed in brain and liver. Expression in the skin is confined to the suprabasal layers of the epidermis and to the hair follicles. {ECO:0000269|PubMed:12175488, ECO:0000269|PubMed:18288204}.
Induction:
Developmental stage:At 15.5 dpc isoform 1 is expressed predominantly in the skin and in the developing hair germ, isoform 2 is expressed predominantly in the epidermis. {ECO:0000269|PubMed:12175488, ECO:0000269|PubMed:18288204}.
Protein families:Grh/CP2 family, Grainyhead subfamily