MLRV_MOUSE   P51667


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UniProt:P51667

Recommended name:Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

EC number:

Alternative names:(MLC-2) (MLC-2v) (Myosin light chain 2, slow skeletal/ventricular muscle isoform) (MLC-2s/v)

Cleaved into:

GeneID:17906

Gene names  (primary ):Myl2

Gene names  (synonym ):Mylpc

Gene names  (ORF ):

Length:166

Mass:18864

Sequence:MAPKKAKKRIEGGSSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGSLKADYVREMLTTQAERFSKEEIDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD

Tissue specificity:Abundantly expressed in both cardiac and slow skeletal muscle (PubMed:1379240). In the adult heart, the phosphorylated form is highly expressed in epicardium and weakly in endocardium (PubMed:22426213). {ECO:0000269|PubMed:1379240, ECO:0000269|PubMed:22426213}.

Induction:

Developmental stage:At 8 dpc highly expressed in the ventricular portion of the heart tube, with no detectable expression in the atrial or sinus venosus regions; also expressed in the proximal outflow tract of the heart tube at minimally detectable levels. At 9-10 dpc expression is well established in the proximal outflow tract region adjacent to the ventricular segment. At 11 dpc, expression becomes restricted to the ventricular region. {ECO:0000269|PubMed:8506363}.

Protein families:


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