PADI6_MOUSE Q8K3V4
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UniProt:Q8K3V4
Recommended name：Protein-arginine deiminase type-6
EC number：EC 3.5.3.15
Alternative names：(Arginine deiminase-like protein) (Egg and embryo abundant PAD) (ePAD) (Peptidylarginine deiminase VI) (Protein-arginine deiminase type VI)
Cleaved into：
GeneID：242726
Gene names (primary )：Padi6
Gene names (synonym )：Pad6 Padi5
Gene names (ORF )：
Length：682
Mass：76778
Sequence：MSFQNSLSLSLVNPTHALCMVGMEITLDISKCAPDKCKSFTIRGSPRILIHISSSVIAGKEDTVVWRSMNHPTVALVRMVAPSPTVDEDKVLVSYFCPDQEVPTATAVLFLTGIEISLEADIYRDGQLDMPSDKQAKKKWMWGMNGWGAILLVNCSPNAVGQPDEQSFQEGPREIQNLSQMNVTVEGPTSILQNYQLILHTSEEEAKKTRVYWSQRGSSAYELVVGPNKPVYLLPTFENRRKEAFYVEATEFPSPSFSGLISLSLSLVEKAHDECIPEIPLYKDTVMFRVAPYIFMPSTQMPLEVYLCRELQLQGFVDSVTKLSEKSKVQVVKVYEDPNRQSKWLQDEMAFCYTQAPHKTVSLILDTPRVSKLEDFPMKYTLTPGSGYLIRQTEDHRVASLDSIGNLMVSPPVKAQGKDYPLGRVLIGGSFYPSSEGRDMNKGLREFVYAQQVQAPVELFSDWLMTGHMDQFMCFVPTNDKNNDQKDFRLLLASPSACFELFEQKQKEGYGNVTLFEDIGAEQLLSNGRESKTISQILADKSFREQNTYVEKCISLNRTLLKTELGLEDKDIILIPQLFCLEQLTNVPSNQQSTKLFARPYFPDMLQIIVLGKNLGIPKPFGPKINGTCCLEEKVCGLLEPLGLKCTFIDDFDCYLANIGDVCASAIINRVPFAFKWWKMTP
Tissue specificity：Expressed at very high levels in oocytes. Weakly expressed in testis. Expressed in primordial, primary, secondary and Graafian follicles, and in immature oocytes, mature eggs and blastocyst (at protein level). {ECO:0000269|PubMed:12654293}.
Induction：
Developmental stage：Detected in developing oocytes and early embryo. Detected in immature-germinal vesicle-stage oocytes, mature metaphase II arrested eggs and pronuclear zygotes, 2-cell, 4-cell and morula stages. Expression decreases in blastocyst stage. {ECO:0000269|PubMed:12654293}.
Protein families：Protein arginine deiminase family