GDF10_MOUSE P97737
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UniProt:P97737
Recommended name:Growth/differentiation factor 10
EC number:
Alternative names:(GDF-10) (Bone morphogenetic protein 3B) (BMP-3B)
Cleaved into:
GeneID:14560
Gene names (primary ):Gdf10
Gene names (synonym ):Bmp3b
Gene names (ORF ):
Length:476
Mass:52575
Sequence:MAPGPARISLGSQLLPMVPLLLLLRGAGCGHRGPSWSSLPSAAAGLQGDRDSQQSPGDAAAALGPGAQDMVAIHMLRLYEKYNRRGAPPGGGNTVRSFRARLEMIDQKPVYFFNLTSMQDSEMILTAAFHFYSEPPRWPRAREVFCKPRAKNASCRLLTPGLPARLHLIFRSLSQNTATQGLLRGAMALTPPPRGLWQAKDISSIIKAARRDGELLLSAQLDTGEKDPGVPRPSSHMPYILVYANDLAISEPNSVAVSLQRYDPFPAGDFEPGAAPNSSADPRVRRAAQVSKPLQDNELPGLDERPAPALHAQNFHKHEFWSSPFRALKPRTGRKDRKKKDQDTFTAASSQVLDFDEKTMQKARRRQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIVPGIPEPCCVPDKMNSLGVLFLDENRNAVLKVYPNMSVETCACR
Tissue specificity:Highly expressed in epididymal adipose tissue, brain, bone and aorta and to a lesser extent in liver and spleen. Expressed at higher levels in preadipocytes than in mature adipocytes (PubMed:21712809). Strongly expressed in glial cells of the cerebellum (PubMed:24963847). {ECO:0000269|PubMed:10419686, ECO:0000269|PubMed:22155034, ECO:0000269|PubMed:24963847, ECO:0000269|PubMed:8679252}.
Induction:
Developmental stage:During embryogenes is expressed most prominently in developing skeletal structures both in the craniofacial region and in the vertebral column. {ECO:0000269|PubMed:10419686}.
Protein families:TGF-beta family