GDF10_MOUSE   P97737


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UniProt:P97737

Recommended name:Growth/differentiation factor 10

EC number:

Alternative names:(GDF-10) (Bone morphogenetic protein 3B) (BMP-3B)

Cleaved into:

GeneID:14560

Gene names  (primary ):Gdf10

Gene names  (synonym ):Bmp3b

Gene names  (ORF ):

Length:476

Mass:52575

Sequence:MAPGPARISLGSQLLPMVPLLLLLRGAGCGHRGPSWSSLPSAAAGLQGDRDSQQSPGDAAAALGPGAQDMVAIHMLRLYEKYNRRGAPPGGGNTVRSFRARLEMIDQKPVYFFNLTSMQDSEMILTAAFHFYSEPPRWPRAREVFCKPRAKNASCRLLTPGLPARLHLIFRSLSQNTATQGLLRGAMALTPPPRGLWQAKDISSIIKAARRDGELLLSAQLDTGEKDPGVPRPSSHMPYILVYANDLAISEPNSVAVSLQRYDPFPAGDFEPGAAPNSSADPRVRRAAQVSKPLQDNELPGLDERPAPALHAQNFHKHEFWSSPFRALKPRTGRKDRKKKDQDTFTAASSQVLDFDEKTMQKARRRQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIVPGIPEPCCVPDKMNSLGVLFLDENRNAVLKVYPNMSVETCACR

Tissue specificity:Highly expressed in epididymal adipose tissue, brain, bone and aorta and to a lesser extent in liver and spleen. Expressed at higher levels in preadipocytes than in mature adipocytes (PubMed:21712809). Strongly expressed in glial cells of the cerebellum (PubMed:24963847). {ECO:0000269|PubMed:10419686, ECO:0000269|PubMed:22155034, ECO:0000269|PubMed:24963847, ECO:0000269|PubMed:8679252}.

Induction:

Developmental stage:During embryogenes is expressed most prominently in developing skeletal structures both in the craniofacial region and in the vertebral column. {ECO:0000269|PubMed:10419686}.

Protein families:TGF-beta family


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