ERR1_MOUSE O08580
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UniProt:O08580
Recommended name:Steroid hormone receptor ERR1
EC number:
Alternative names:(Estrogen receptor-like 1) (Estrogen-related receptor alpha) (ERR-alpha) (Nuclear receptor subfamily 3 group B member 1)
Cleaved into:
GeneID:26379
Gene names (primary ):Esrra
Gene names (synonym ):Err1 Estrra Nr3b1
Gene names (ORF ):
Length:422
Mass:45464
Sequence:MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVTLASGPAPARCLPGHKEEEDGEGAGSGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD
Tissue specificity:Most highly expressed in kidney, heart, and brown adipocytes. Also found in uterus, cervix and vagina.
Induction:Activated by diethylstilbestrol (DES) and estradiol in the uterus.
Developmental stage:Expressed in an organ specific manner through mid- to late embryonic development with persistent high-level expression in brown adipose tissue and intestinal mucosa.
Protein families:Nuclear hormone receptor family, NR3 subfamily