SYNB_MOUSE   Q8BI41


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UniProt:Q8BI41

Recommended name:Syncytin-B [Cleaved into: Surface protein

EC number:

Alternative names:(SU); Transmembrane protein (TM)]

Cleaved into:

GeneID:239167

Gene names  (primary ):Synb

Gene names  (synonym ):

Gene names  (ORF ):

Length:618

Mass:69514

Sequence:MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT

Tissue specificity:Highly expressed in placenta where it localizes to syncytiotrophoblasts of the labyrinthine zona (PubMed:15644441). Specifically localizes to syncytiotrophoblast layer II (SynT-II) (PubMed:18448564). Also detected at very low levels in ovary (PubMed:15644441). {ECO:0000269|PubMed:15644441, ECO:0000269|PubMed:18448564}.

Induction:In males, up-regulated in regenerating muscle tissue after injury. {ECO:0000269|PubMed:27589388}.

Developmental stage:Expressed in the placental labyrinth from stage 8.5 dpc onwards. {ECO:0000269|PubMed:18448564}.

Protein families:Gamma type-C retroviral envelope protein family


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