SYNB_MOUSE Q8BI41
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UniProt:Q8BI41
Recommended name:Syncytin-B [Cleaved into: Surface protein
EC number:
Alternative names:(SU); Transmembrane protein (TM)]
Cleaved into:
GeneID:239167
Gene names (primary ):Synb
Gene names (synonym ):
Gene names (ORF ):
Length:618
Mass:69514
Sequence:MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT
Tissue specificity:Highly expressed in placenta where it localizes to syncytiotrophoblasts of the labyrinthine zona (PubMed:15644441). Specifically localizes to syncytiotrophoblast layer II (SynT-II) (PubMed:18448564). Also detected at very low levels in ovary (PubMed:15644441). {ECO:0000269|PubMed:15644441, ECO:0000269|PubMed:18448564}.
Induction:In males, up-regulated in regenerating muscle tissue after injury. {ECO:0000269|PubMed:27589388}.
Developmental stage:Expressed in the placental labyrinth from stage 8.5 dpc onwards. {ECO:0000269|PubMed:18448564}.
Protein families:Gamma type-C retroviral envelope protein family